101 HARLEY STREET | LONDON W1G 6AH | | +44 020 3725 0800

Sykle Longevity Clinic Logo - Doctor-led regenerative medicine in the UK

ADVANCING
HEALTH.

EXTENDING
LIFE.

IN AN AGE OF RAPIDLY PROGRESSING ADVANCES IN KNOWLEDGE, SCIENCE AND AI, INCREASINGLY, WE CAN TREAT NOT ONLY WHAT HAS ALREADY HAPPENED, BUT ALSO PREVENT WHAT MIGHT HAPPEN.

WHAT DOES LONGEVITY HEALTHCARE REALLY MEAN?

At sykle.life, it is not simply about adding years to life, it’s also about adding life to years – preserving health, capability and independence so that life remains active, engaged, and meaningful over time.

We combine extensive medical experience with leading-edge science and technologies to support both a longer lifespan and an optimised healthspan, the quality of how we live, move, think, and connect as we age.

Decades of clinical practice have reinforced one fundamental and unarguable truth – health is deeply personal.

Our focus is not on quick fixes or exaggerated claims, but on understanding the biology of ageing and slowing its impact responsibly.

Through this approach, we aim to support strength, cognitive clarity, resilience, and independence for as long as possible.

WHAT MAKES SYKLE.LIFE DIFFERENT?

Longevity medicine is a rapidly developing field. At sykle.life, our focus is on providing thoughtful, medically grounded care that helps individuals better understand the factors influencing their long-term health.

Our approach combines clinical expertise, advanced diagnostics, and personalised strategies designed to support health across the decades ahead.

HOW YOUR ASSESSMENT WORKS

Your personalised health assessment follows a structured two-step process, designed to provide a comprehensive understanding of your health and the factors influencing long-term wellbeing.

Each process is designed to build a clearer picture of your health profile and translate those insights into practical, evidence-informed recommendations.

PRE‑CONSULTATION HEALTH ASSESSMENT

Prior to your appointment, you will receive a confidential pre‑consultation health assessment designed to provide our clinical team with a comprehensive understanding of your current health profile.

This structured questionnaire allows us to review key aspects of your medical background in advance, including your medical and surgical history, current medications and supplements, allergies, and any symptoms or concerns you may wish to discuss and supplements or medications you wish to explore.

We also gather information relating to lifestyle and environmental factors that influence long‑term health, including sleep quality, nutrition, physical activity, alcohol consumption, smoking status, and other relevant exposures. Your family medical history is considered in detail, with particular attention to hereditary patterns associated with cardiovascular disease, cancer, metabolic conditions, and neurodegenerative disorders.

You will also be invited to outline your personal health priorities and longevity goals. This ensures your consultation and assessment are thoughtfully aligned with what matters most to you, allowing our clinicians to tailor their evaluation and recommendations accordingly.

CLINICAL CONSULTATION AND EXAMINATION

Your appointment begins with a comprehensive consultation with one of our physicians, providing dedicated time to explore your health history, current concerns, and long‑term wellbeing objectives.

During this discussion, your pre‑submitted health assessment will be reviewed in detail, enabling a deeper understanding of your medical background and lifestyle factors that may influence your future health trajectory.

The consultation is followed by a clinical examination. Anthropometric measurements are taken including hand grip strength and detailed body composition. Vital signs are recorded including, blood pressure, heart rate and lung function. A routine urinalysis is also performed to screen for markers such as protein, glucose, blood, and indicators of infection.

Where appropriate and guided by the information provided within your health assessment, your physician may recommend additional investigations or diagnostic testing to further refine your evaluation.

A comprehensive panel of blood tests to assess key biomarkers of general health, and age-related disease risk. These include full blood count and haematology – to detect anaemia, infection, clotting disorders, or abnormal cell lines.

  • Liver and Kidney Function
    To assess detoxification, metabolism, and filtration capacity.
  • Glucose and Insulin Markers
    Including fasting glucose, fasting insulin, HbA1c, and HOMA-IR, to assess metabolic health, insulin resistance and diabetes risk.
  • Lipid and Cardiovascular Risk Profile
    Including cholesterol subtypes, Apolipoprotein B, Lipoprotein(a), Lp-PLA2 (PLAC) blood test and high-sensitivity CRP.
  • Vitamin and Mineral Levels
    Including Vitamin D, B12, folate, magnesium, calcium, phosphate, iron studies, and zinc.
  • Hormonal Profile
    With measurement of cortisol, DHEA, IGF-1, oestrogen, testosterone, SHBG, LH, and FSH.
  • Inflammatory Markers
    Including ESR and hs-CRP
  • Tumour Markers
    CEA, CA125, CA19-9 and PSA (for men).

Additional insights into structural health, vascular integrity, and early disease processes not detectable through other investigations. These studies are arranged selectively, guided by risk factors and clinical judgement, and are offered as optional enhancements to the core assessments.

CT Lung Scan
A CT scan of the lungs to identify small pulmonary nodules or early changes not visible on standard chest X-ray. This may assist in the early detection of lung cancer or pre-cancerous changes, as well as evidence of chronic lung disease or prior injury.

Carotid Doppler Ultrasound
A non-invasive ultrasound assessment of the carotid arteries to identify atherosclerotic plaque and vascular narrowing. Carotid disease is a recognised marker of systemic cardiovascular risk and may inform stroke prevention strategies.

CT Coronary Calcium Scan
A gold-standard assessment of coronary artery calcification, providing a quantitative measure of atherosclerotic burden. This scan offers valuable long-term cardiovascular risk stratification, particularly in individuals without symptoms.

CT Coronary Angiography (CTCA)
CT coronary angiography allows visualisation of coronary arteries, plaque, and any narrowing that may impair blood flow. This can be performed alongside a coronary calcium scan.

Exercise Echocardiogram
A specialist ultrasound to produce moving images of the heart’s function during exercise.

24-Hour Blood Pressure Monitor
To diagnose hypertension and any anomalies.

MRI & MRA Brain Scan
Magnetic resonance imaging of the brain and cerebral blood vessels to identify structural or vascular abnormalities. This may detect early cerebrovascular disease, tumours, aneurysms, or other conditions associated with cognitive decline or neurological risk.

Thyroid Ultrasound
An ultrasound assessment of the thyroid gland to evaluate nodules or structural abnormalities, including those that may warrant further investigation.

Abdominal MRI Scan
High-resolution imaging of abdominal organs, including the liver, kidneys, pancreas, adrenal glands, spleen, and gall bladder. This scan may identify structural disease or early malignancy, including cancers that often remain clinically silent until advanced stages.

Bone Mineral Density (DEXA) Scan
A low-dose X-ray assessment of bone density to evaluate skeletal strength and fracture risk. This investigation assists in the early identification of osteoporosis or accelerated bone loss.

Mammography
A breast imaging study designed to detect early signs of breast cancer, often before clinical changes become apparent. Mammography remains an important tool in risk-based breast health assessment.

Pelvic Scan
A non-invasive diagnostic exam that produces images that are used to assess organs and structures within the female pelvis. A pelvic scan allows quick visualisation of the female pelvic organs and structures including the uterus, cervix, vagina, fallopian tubes and ovaries.

Prostate Multiparametric MRI (mpMRI)
Gold-standard for prostate assessment using multiple imaging sequences to improve detection and characterisation of clinically significant prostate cancer, beyond the capabilities of standard MRI.

Testicular Ultrasound
A focused ultrasound examination of the testes, typically considered in younger men where there are symptoms, examination concerns, or relevant risk factors.

Vo2 Max Testing
This is a gold-standard assessment of cardiorespiratory fitness. Quantifying the maximum amount of oxygen your body can use during exercise, it is a strong independent predictor of cardiovascular health, metabolic efficiency, and all-cause mortality. Results are interpreted against age- and sex-matched reference data, with individualised feedback on training zones.

FEES AND MEMBERSHIP

Initial Assessment and Appraisal:

£500

Extensive Blood Test Profile:

£700

Advanced Diagnostic Imaging, Procedures and Investigations:

Subject to Request

Costs exclude medications and supplements, which are prescribed according to each patient’s individual clinical profile and diagnostic findings.

A limited number of annual memberships are available for individuals, families, and corporate clients seeking a fully bespoke and proactive approach to health and longevity. Each programme includes quarterly physician-led health reviews, advanced blood analysis,  premium therapeutic supplementation, and individually prescribed oral medications.

WANT TO KNOW MORE?

For more information about our services or to arrange a consultation, please complete the form below or contact us directly at concierge@sykle.life or +44 020 3725 0800.
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